Pharmanotes: Benazepril

Benazepril (Lotensin) is an ACE inhibitor indicated for hypertension. Similar to its relatives lisinopril and enalapril, benazepril reduces the activity of the renin-angiotensin-aldosterone system, which results in vasodilation and lower blood pressure.


This has been a post in the Pharmanotes series, which seeks to educate the public on the “Top 200” most prescribed medications. The contents within this post are scholarly and do not constitute as medical advice.


Following through on medicine safety concerns

The mother of an 8-month-old girl was given a prescription for her baby for amoxicillin 400 mg twice daily. Amoxicillin is an antibiotic commonly used to treat various ear, nose, throat, chest, and skin infections. When dropping off the prescription at the pharmacy, a pharmacist asked the mother for the child’s weight, which was 20 pounds. When the mother picked up the medicine, the pharmacist gave her a 5 mL syringe to use to draw up each dose of the liquid medicine. The directions on the prescription said, “Amoxicillin (400 mg/5 mL), give 12 mL twice a day.” The pharmacist told the mother to give her child two full syringes of the medicine (5 mL each), and then 2 mL of another syringe of medicine.

via Following through on medicine safety concerns. Continue reading

Pharmacy Boss Steals 200K Oxycodone Pills, Faces Life In Prison

City Special Narcotics Prosecutor Bridget Brennan’s office is still investigating what became of the drugs but believe they ended up on the thriving black market for prescription painkillers, where the more than 193,000 missing pills could fetch a total of about $5.6 million.

While serving as Mount Sinai Beth Israel’s pharmacy director for 14 years before his firing this spring, D’Alessando exploited his access to the hospital’s drug vault to grab oxycodone pills by the score: about 100 at a time when he started in January 2009, but 1,500 at a go by the time the scheme came to light this spring, said Kati Cornell, a spokeswoman for Brennan. Hospital officials first approached him April 1 about the disappearing drugs, and he signed out another 1,500 pills the next day, she said.

To account for the missing medicine, D’Alessandro made phony entries in an electronic inventory system to indicate that the drugs were being sent to a research pharmacy within the hospital, prosecutors said. The pharmacy wasn’t doing any oxycodone research at the time, and its staffers were unaware of the phony requisition slips, according to prosecutors.

via Pharmacy Boss Accused of Stealing 200,000 Oxy Pills « KRON4 – San Francisco Bay Area News. Continue reading

Pharmanotes: Lisinopril

Lisinopril (Prinivil, Zestoril) is an ACE inhibitor indicated for hypertension and congestive heart failure. Like enalapril, lisinopril works by reducing the activity of the renin-angiotensin-aldosterone system, which leads to blood vessel dilation and an associated drop in blood pressure. Lisinopril is typically dosed once daily, as it has a longer half-life than enalapril.

This has been a post in the Pharmanotes series, which seeks to educate the public on the “Top 200” most prescribed medications. The contents within this post are scholarly and do not constitute as medical advice.

Compounding Pharmacies Offer Alternatives in Medical Diagnostics

Hospitals are beginning to explore and use alternatives to two manufactured radiotracers that both saw major price increases earlier this year.

Canadian radiopharmaceutical firm Jubilant DraxImage announced at the end of February that it was increasing the prices of macroaggregated albumin (MAA) and diethylenetriamine pentaacetate (DTPA), which are used for ventilation/perfusion (V/Q) scans to diagnose or rule out a pulmonary embolism.

The company, which had announced a shortage of MAA last September, said the previous prices had not covered production costs or allowed for any manufacturing improvements, putting the long-term availability of MAA and DTPA at risk. Some facilities are investigating custom MAA vials from compounding pharmacies, which work directly with prescribers to prepare personalized medications for patients, at a lower cost than the commercial kits. AnazaoHealth Corp., a specialty pharmacy headquartered in Tampa, Fla., that serves the nuclear medicine market, has seen more interest in the product.

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Evening News: Pharmacy and pharmacist have licenses suspended

Megs Discount Pharmacy, along with its owner Susan Jenevive Megwa, have been under investigation by Denton police for more than two years. As a result of the investigation, the pharmacy license for Megs Discount Pharmacy and the pharmacist license for Susan Megwa, the sole pharmacist at Megs, were suspended by the state board’s disciplinary panel Friday.

Allison Benz, director of professional services for the Texas State Board of Pharmacy, said in an email Tuesday that the applications for temporary suspension were granted because the evidence and information reviewed indicated that the operation of Megs Discount Pharmacy, as well as the pharmacy practice of Megwa, posed a continuing threat to the public’s welfare.

The delivery of hydrocodone and alprazolam to an informant without prescriptions, non-therapeutic dispensing of hydrocodone to three patients and audit shortages of hydrocodone and alprazolam contributed to each of the 90-day license suspensions, Benz said.

via Pharmacy and pharmacist have licenses suspended | Denton Record Chronicle | News for Denton County, Texas.